Article
Evaluation of serum SLCO1B1 levels and genetic variants of SLCO1B1 rs4149056 and rs2306283 in patients with early and exudative age-related macular degeneration.
Gene - 15 Nov 2018
Liutkeviciene Rasa, Vilkeviciute Alvita, Slavinskaite Aiste, Petrauskaite Aiste, Tatarunas Vacis, Kriauciuniene Loresa
Abstract excerpt
PURPOSE: To determine SLCO1B1 rs4149056 and rs2306283 gene polymorphisms and SLCO1B1 serum levels in patients with early and exudative age-related macular degeneration. MATERIALS AND METHODS: The study enrolled 206 patients with exudative AMD, 253 patients with early AMD and 301 control subjects. DNA was extracted from peripheral venous blood leukocytes using commercial kits. Genotyping of SLCO1B1 rs4149056 and...
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