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Integrated Analysis of Polymerase Family Gene Mutations in Acute Myeloid Leukemia: Clinical Features, Prognosis, and Bioinformatics Insights.

Medicina (Kaunas, Lithuania) - 1 Dec 2024

Wu Jianrong, Wang Chaoban, Tang Wenhao, Gao Ju, Guo Xia

Abstract excerpt

Background and Objectives: The long-term prognosis of acute myeloid leukemia (AML) is challenging due to limited understanding of the molecular markers involved in its development. This study investigates the role of DNA polymerases in AML to offer new insights for diagnosis and treatment. Materials and Methods: A retrospective study on pediatric AML patients with POL gene family mutations from 2021 to 2024 was...

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PMID: 39768855
DOI: 10.3390/medicina60121975

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