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Article

Alpha-Synuclein Effects on Mitochondrial Quality Control in Parkinson’s Disease

22 Dec 2024

Abstract excerpt

The maintenance of healthy mitochondria is essential for neuronal survival and relies upon mitochondrial quality control pathways involved in mitochondrial biogenesis, mitochondrial dynamics, and mitochondrial autophagy (mitophagy). Mitochondrial dysfunction is critically implicated in Parkinson's disease (PD), a brain disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra....

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Share to Autophagy in Disease and Therapy
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PMID: 39766356
DOI: 10.3390/biom14121649

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