Article
Senescence-like Phenotype After Chronic Exposure to Isoproterenol in Primary Quiescent Immune Cells.
Biomolecules - 28 Nov 2024
Laumann Michael, Palombo Philipp, Fieres Judy, Thomas Mara, Saretzki Gabriele, Bürkle Alexander, Moreno-Villanueva Maria
Abstract excerpt
Chronic stress is associated with a higher risk for carcinogenesis as well as age-related diseases and immune dysfunction. There is evidence showing that psychological stress can contribute to premature immunosenescence. Therefore, the question arose whether chronic exposure to catecholamine could drive immune cells into senescence. Peripheral blood mononuclear cells were isolated from whole blood. After repeated...
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