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Chronic stress increases transcriptomic indicators of biological aging in mouse bone marrow leukocytes

11 Apr 2022

Abstract excerpt

Research with animals and humans has demonstrated that chronic stress exposure can impact key biological aging pathways such as inflammation and DNA damage, suggesting a mechanism through which stress may increase risk for age-related disease. However, it is less clear whether these effects extend to other hallmarks of the aging process, such as cellular senescence. Male SCID mice were exposed to 14 days of...

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PMID: 35481228
DOI: 10.1016/j.bbih.2022.100461

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