Article
Genomic analysis of surgical patients to identify patients at risk for postoperative sepsis and surgical site infection.
The journal of trauma and acute care surgery - 1 Mar 2025
Ahmed Kaleem S, Christensen Mathias A, Bonde Alexander, Wei Wei-Qi, Khan Atlas, Pacheco Jennifer, Roy-Puckelwartz Megan, McCarthy Robert J, Alam Hasan B, Sillesen Martin
Abstract excerpt
BACKGROUND: Early and accurate diagnosis of sepsis and the ensuing organ dysfunction remain a challenge in the postoperative setting. Susceptibility to infections, as well as the subsequent immunological response, are driven to some extent by the genetic predisposition of the patient. The purpose of this study was to identify novel genetic variants associated with postoperative sepsis (POS) and surgical site...
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