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Article

Tumor Mutation Signature Reveals the Risk Factors of Lung Adenocarcinoma with EGFR or KRAS Mutation.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000

Wang Jialiang, Guo Chang, Wang Jiexiao, Zhang Xiaopeng, Qi Jian, Huang Xiang, Hu Zongtao, Wang Hongzhi, Hong Bo

Abstract excerpt

INTRODUCTION: EGFR and KRAS mutations are frequently detected in lung adenocarcinoma (LUAD). Tumor mutational signature (TMS) determination is an approach to identify somatic mutational patterns associated with pathogenic factors. In this study, through the analysis of TMS, the underlying pathogenic factors of LUAD with EGFR and KRAS mutations were traced. METHODS: This was a retrospective study. TMS of LUAD with...

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Identifiers

PMID: 39760242
DOI: 10.1177/10732748241307363
PMCID: PMC11701915

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