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Article

Rapid and accurate multi-phenotype imputation for millions of individuals.

Nature communications - 4 Jan 2025

Gu Lin-Lin, Wu Hong-Shan, Liu Tian-Yi, Zhang Yong-Jie, He Jing-Cheng, Liu Xiao-Lei, Wang Zhi-Yong, Chen Guo-Bo, Jiang Dan, Fang Ming

Abstract excerpt

Deep phenotyping can enhance the power of genetic analysis, including genome-wide association studies (GWAS), but the occurrence of missing phenotypes compromises the potential of such resources. Although many phenotypic imputation methods have been developed, the accurate imputation of millions of individuals remains challenging. In the present study, we have developed a multi-phenotype imputation method based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39755672
DOI: 10.1038/s41467-024-55496-0
PMCID: PMC11700122

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