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Article

Integrative analyses of mendelian randomization and bioinformatics reveal casual relationship and genetic links between COVID-19 and knee osteoarthritis.

BMC medical genomics - 2 Jan 2025

Zheng Xiao, Li Jinhao, Ma Qinfeng, Gong Jianping, Pan Jianbo

Abstract excerpt

BACKGROUND: Clinical and epidemiological analyses have found an association between coronavirus disease 2019 (COVID-19) and knee osteoarthritis (KOA). Infection with COVID-19 may increase the risk of developing KOA. OBJECTIVES: This study aimed to investigate the potential causal relationship between COVID-19 and KOA using Mendelian randomization (MR) and to explore the underlying mechanisms through a systematic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39748395
DOI: 10.1186/s12920-024-02074-4
PMCID: PMC11697936

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