Interleukin-33 gene polymorphisms and chronic obstructive pulmonary disease in the Chinese Han population.

Abstract excerpt

OBJECTIVE: To investigate the relationship between interleukin (IL)-33 gene polymorphisms rs928413 and rs7044343 with chronic obstructive pulmonary disease (COPD) in the Chinese Han population. METHOD: We assessed IL-33 rs928413 and rs7044343 polymorphisms by Sanger sequencing of PCR products amplified from the genomic DNA of 160 COPD patients and 123 healthy controls. RESULTS: There was no significant difference...