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Identification of the shared gene signatures in retinoblastoma and osteosarcoma by machine learning

28 Dec 2024

Abstract excerpt

Osteosarcoma (OS) is the most prevalent secondary sarcoma associated with retinoblastoma (RB). However, the molecular mechanisms driving the interactions between these two diseases remain incompletely understood. This study aims to explore the transcriptomic commonalities and molecular pathways shared by RB and OS, and to identify biomarkers that predict OS prognosis effectively. RNA sequences and patient...

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PMID: 39733097
DOI: 10.1038/s41598-024-82789-7

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