Article
Whole-genome Sequencing Analysis of Bile Tract Cancer Reveals Mutation Characteristics and Potential Biomarkers.
Cancer genomics & proteomics - 1 Jan 2000
Kokuryo Toshio, Sunagawa Masaki, Yamaguchi Junpei, Baba Taisuke, Kawakatsu Shoji, Watanabe Nobuyuki, Onoe Shunsuke, Mizuno Takashi, Ebata Tomoki
Abstract excerpt
BACKGROUND/AIM: Bile tract cancer (BTC) is a malignant tumor with a poor prognosis. Recent studies have reported the heterogeneity of the genomic background and gene alterations in BTC, but its genetic heterogeneity and molecular profiles remain poorly understood. Whole-genome sequencing may enable the identification of novel actionable gene mutations involved in BTC carcinogenesis, malignant progression, and...
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