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Article

Socioeconomic position interacts with the genetic effect of a CRP gene common variant to influence C-reactive protein values.

Scientific reports - 23 Dec 2024

Cheaib Miriam, Hornung Nicola, Dragano Nico, Frank Mirjam, Hoffmann Per, Nöthen Markus M, Erbel Raimund, Stang Andreas, Schmidt Börge

Abstract excerpt

OBJECTIVES: C-Reactive Protein (CRP) values are partly determined by variation at the CRP gene locus, but also influenced by socioeconomic position (SEP) and related lifestyle factors. As gene-by-SEP interactions have been suggested for traits associated with CRP and SEP (e.g., BMI, coronary artery disease), the aim of this study was to investigate the strength of a possible interaction between a CRP gene common...

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Identifiers

PMID: 39715856
DOI: 10.1038/s41598-024-83437-w
PMCID: PMC11666539

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