Article
A genetic risk score of alleles related to MGUS interacts with socioeconomic position in a population-based cohort.
Scientific reports - 15 Mar 2022
Baak Lisa, Frank Mirjam, Dürig Jan, Dührsen Ulrich, Hoffmann Per, Nöthen Markus M, Dragano Nico, Erbel Raimund, Jöckel Karl-Heinz, Schmidt Börge
Abstract excerpt
Environmental, genetic, and social factors are suggested to jointly influence monoclonal gammopathy of undetermined significance (MGUS), a precursor of multiple myeloma. Aim of this study was to investigate interactions between MGUS-related genetic variants and socioeconomic position (SEP) indicators education and income on MGUS in a population-based study. Two different MGUS-related genetic risk allele sum...
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