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Association Between Stress‐Induced Weight Loss and Autophagy‐Related Gene Expression in the Hippocampus and Midbrain of Depression Model Mice

23 Dec 2024

Abstract excerpt

AIM: Recent studies have implicated autophagy in both weight regulation and depression. This study aimed to investigate the relationship between stress-induced weight loss and autophagy-related gene expression in a mouse model of depression. METHOD: Male C57BL/6 mice were subjected to a chronic immobilization stress (CIS) protocol for 14 days to induce depressive-like behavior. Body weight was measured before and...

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PMID: 39715728
DOI: 10.1002/npr2.12515

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