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Tissue-based Gene Expression Diagnosis of Mild and Moderate T-cell-mediated Rejection to Guide Therapy in Kidney Transplants

23 Dec 2024

Abstract excerpt

BACKGROUND: Mild histologic lesions of tubulo-interstitial inflammation could represent a "response-to-wounding" rather than allorecognition. Tissue gene expression may complement histopathology for T-cell-mediated rejection (TCMR) diagnostics. METHODS: We report on the incorporation of tissue gene expression testing using a Molecular Microscope Diagnostic System into the management of kidney transplant biopsies...

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Share to Infectious Disease Case Reports and Treatments
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PMID: 39710875
DOI: 10.1097/tp.0000000000005296

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