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Article

One-Pot Assay Based on CRISPR/Cas13a Technology for HEV RNA Point-of-Care Testing.

Journal of medical virology - 1 Dec 2024

Fan Zihao, Xu Ling, Cao Yaling, Liu Tianxu, Tian Yuan, Pan Zhenzhen, Mo Yinkang, Wang Xinyu, Zhu Xianru, Gao Yao, Zhang Xiangying, Pan Calvin Q, Wang Lin, Ren Feng

Abstract excerpt

Hepatitis E virus (HEV) poses a serious threat to both public health and animal food safety, thereby highlighting the demands for rapid, sensitive, and easy-to-use detection. This study aimed to develop a One-Pot assay using CRISPR/Cas13a for detecting HEV RNA, suitable for point-of-care testing (POCT) in resource-limited settings. CRISPR/Cas13a combined with reverse transcription polymerase chain reaction...

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Share to RNA, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39704190
DOI: 10.1002/jmv.70115
PMCID: PMC11660031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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