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One-tube SARS-CoV-2 detection platform based on RT-RPA and CRISPR/Cas12a

16 Feb 2021

Abstract excerpt

BACKGROUND: COVID-19 has spread rapidly around the world, affecting a large percentage of the population. When lifting certain mandatory measures for an economic restart, robust surveillance must be established and implemented, with nucleic acid detection for SARS-CoV-2 as an essential component. METHODS: We tried to develop a one-tube detection platform based on RT-RPA (Reverse Transcription and Recombinase...

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Biosensors and Analytical Detection
CRISPR and Genetic Engineering
SARS-CoV-2 detection and testing

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33593370
DOI: 10.1186/s12967-021-02741-5

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