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LncRNAs induce oxidative stress and spermatogenesis by regulating endoplasmic reticulum genes and pathways

6 May 2021

Abstract excerpt

Oligozoospermia or low sperm count is a leading cause of male infertility worldwide. Despite decades of work on non-coding RNAs (ncRNAs) as regulators of spermatogenesis, fertilization, and male fertility, the literature on the function of long non-coding RNAs (lncRNAs) in human oligozoospermia is scarce. We integrated lncRNA and mRNA sequencing data from 12 human normozoospermic and oligozoospermic samples and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34001678
DOI: 10.18632/aging.202971

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