Article
Genome-wide expression of azoospermia testes demonstrates a specific profile and implicates ART3 in genetic susceptibility.
PLoS genetics - 1 Feb 2008
Okada Hiroyuki, Tajima Atsushi, Shichiri Kazuyoshi, Tanaka Atsushi, Tanaka Kenichi, Inoue Ituro
Abstract excerpt
Infertility affects about one in six couples attempting pregnancy, with the man responsible in approximately half of the cases. Because the pathophysiology underlying azoospermia is not elucidated, most male infertility is diagnosed as idiopathic. Genome-wide gene expression analyses with microarray on testis specimens from 47 non-obstructive azoospermia (NOA) and 11 obstructive azoospermia (OA) patients were...
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