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Machine learning-based diagnostic model of lymphatics-associated genes for new therapeutic target analysis in intervertebral disc degeneration

4 Dec 2024

Abstract excerpt

Background: Low back pain resulting from intervertebral disc degeneration (IVDD) represents a significant global social problem. There are notable differences in the distribution of lymphatic vessels (LV) in normal and pathological intervertebral discs. Nevertheless, the molecular mechanisms of lymphatics-associated genes (LAGs) in the development of IVDD remain unclear. An in-depth exploration of this area will...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39697339
DOI: 10.3389/fimmu.2024.1441028

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