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In vitro model of retinoblastoma derived tumor and stromal cells for tumor microenvironment (TME) studies

18 Dec 2024

Abstract excerpt

Retinoblastoma (RB) is an intraocular tumor arising from retinal cone progenitor cells affecting young children. In the last couple of years, RB treatment evolved towards eye preserving therapies. Therefore, investigating intratumoral differences and the RB tumor microenvironment (TME), regulating tumorigenesis and metastasis, is crucial. How RB cells and their TME are involved in tumor development needs to be...

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PMID: 39695086
DOI: 10.1038/s41419-024-07285-2

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