Article
Pharmacogenetics of dabigatran and apixaban in association with gastrointestinal bleeding.
Neuro endocrinology letters - 28 Nov 2024
Veleta Tomas, Beranek Martin, Tacheci Ilja, Dulicek Petr, Maly Radovan, Cermakova Eva, Soukup Tomas
Abstract excerpt
OBJECTIVES: To determine whether selected single nucleotide polymorphisms (SNPs) of genes encoding proteins responsible for the activation, transport, or metabolism of dabigatran and apixaban might be associated with a risk of gastrointestinal bleeding in a cohort of adult patients treated with these drugs. No previous study has focused specifically on the association with gastrointestinal bleeding. MATERIALS AND...
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