Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibroblast Heterogeneity in Inflammatory Bowel Disease

3 Dec 2024

Abstract excerpt

Intestinal fibroblasts are pivotal players in maintaining tissue homeostasis and orchestrating responses to injury and inflammation within the gastrointestinal (GI) tract. Fibroblasts contribute significantly to the pathogenesis of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis (UC), by secreting pro-inflammatory cytokines, modulating immune cell activity, and promoting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibroblast Growth Factor Research
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Pancreatitis Pathology and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39684719
DOI: 10.3390/ijms252313008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibroblast Heterogeneity in Inflammatory Bowel DiseasePMID 39684719Read ↗

The diverse nature of intestinal fibroblasts in development, homeostasis, and diseaseSemantic proximity Read ↗

Novel fibroblast phenotypes in homeostasis and chronic inflammation: From functions to potential regulators.Semantic proximity Read ↗

Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healingSemantic proximity Read ↗

Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodelingSemantic proximity Read ↗

Mapping mesenchymal diversity in the developing human intestine and organoidsSemantic proximity Read ↗

Fibroblast heterogeneity: Keystone of tissue homeostasis and pathology in inflammation and ageingSemantic proximity Read ↗

Cellular complexity and crosstalk in murine TNF-dependent ileitis: Different fibroblast subsets propel spatially defined ileal inflammation through TNFR1 signallingSemantic proximity Read ↗

Stricturing Crohn’s disease single-cell RNA sequencing reveals fibroblast heterogeneity and intercellular interactionsSemantic proximity Read ↗

Fibroblast pathology in inflammatory joint diseaseSemantic proximity Read ↗

High-resolution integrative analysis allows characterization and spatial annotation of normal and cancer-associated colon fibroblastsSemantic proximity Read ↗

Fibroblasts in Orchestrating Colorectal Tumorigenesis and ProgressionSemantic proximity Read ↗

Gastrointestinal Fibroblasts Have Specialized, Diverse Transcriptional Phenotypes: A Comprehensive Gene Expression Analysis of Human Fibroblasts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.