Article
The CALERIE Genomic Data Resource.
Nature aging - 1 Feb 2025
Ryan C P, Corcoran D L, Banskota N, Eckstein Indik C, Floratos A, Friedman R, Kobor M S, Kraus V B, Kraus W E, MacIsaac J L, Orenduff M C, Pieper C F, White J P, Ferrucci L, Horvath S, Huffman K M, Belsky D W
Abstract excerpt
Caloric restriction (CR) slows biological aging and prolongs healthy lifespan in model organisms. Findings from the CALERIE randomized, controlled trial of long-term CR in healthy, nonobese humans broadly supports a similar pattern of effects in humans. To expand our understanding of the molecular pathways and biological processes underpinning CR effects in humans, we generated a series of genomic datasets from...
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