Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calorie restriction modulates the transcription of genes related to stress response and longevity in human muscle: The CALERIE study

12 Oct 2023

Abstract excerpt

The lifespan extension induced by 40% caloric restriction (CR) in rodents is accompanied by postponement of disease, preservation of function, and increased stress resistance. Whether CR elicits the same physiological and molecular responses in humans remains mostly unexplored. In the CALERIE study, 12% CR for 2 years in healthy humans induced minor losses of muscle mass (leg lean mass) without changes of muscle...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Muscle Physiology and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37823711
DOI: 10.1111/acel.13963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calorie restriction modulates the transcription of genes related to stress response and longevity in human muscle: The CALERIE studyPMID 37823711Read ↗

The CALERIE Genomic Data Resource.Semantic proximity Read ↗

The CALERIE™ Genomic Data ResourceSemantic proximity Read ↗

Calorie restriction in humans inhibits the <scp>PI</scp>3<scp>K</scp>/<scp>AKT</scp> pathway and induces a younger transcription profileSemantic proximity Read ↗

Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and WomenSemantic proximity Read ↗

EFFECTS OF 12 MONTHS OF CALORIC RESTRICTION ON MUSCLE MITOCHONDRIAL FUNCTION IN HEALTHY INDIVIDUALSSemantic proximity Read ↗

Unravelling the Transcriptomic Symphony of Sarcopenia: Key Pathways and Hub Genes Altered by Muscle Ageing and Caloric Restriction Revealed by RNA SequencingSemantic proximity Read ↗

Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading StatesSemantic proximity Read ↗

Caloric restriction reprograms adipose tissues in rhesus monkeysSemantic proximity Read ↗

Calorie restriction reduces biomarkers of cellular senescence in humansSemantic proximity Read ↗

Temporal dynamics of the multi-omic response to endurance exercise training across tissuesSemantic proximity Read ↗

Calorie Restriction Increases Muscle Mitochondrial Biogenesis in Healthy HumansSemantic proximity Read ↗

Integrative Multi-omics Analysis of the Human Skeletal Muscle Response to Endurance or Resistance Exercise: Findings from the Molecular Transducers of Physical Activity Consortium (MoTrPAC)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.