Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial transplantation rescues Ca2+ homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy

1 Dec 2024

Abstract excerpt

homeostasis imbalance in SLC25A3-KO hiPSC-CMs. Finally, we explored the prospective therapeutic implications of mitochondrial transplantation in rescuing SLC25A3-related HCM.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy and Myosin Studies
Share to Genetics and Neurodevelopmental Disorders
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39671292
DOI: 10.1016/j.celrep.2024.115065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 11 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial transplantation rescues Ca2+ homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathyPMID 39671292Read ↗

Metabolic remodeling and calcium handling abnormality in induced pluripotent stem cell-derived cardiomyocytes in dilated phase of hypertrophic cardiomyopathy with MYBPC3 frameshift mutationSemantic proximity Read ↗

Cardiomyopathy phenotypes caused by a heterozygous MYBPC3 mutation revealed in different hiPSC cardiac models.Semantic proximity Read ↗

The p.H222P lamin A/C mutation induces heart failure via impaired mitochondrial calcium uptake in human cardiac laminopathySemantic proximity Read ↗

Hypertrophic cardiomyopathy-linked mutation in troponin T causes myofibrillar disarray and pro-arrhythmic action potential changes in human iPSC cardiomyocytes.Semantic proximity Read ↗

Establishing a new human hypertrophic cardiomyopathy-specific model using human embryonic stem cells.Semantic proximity Read ↗

Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function.Semantic proximity Read ↗

Molecular Rewiring in TNNT2-Linked Hypertrophic Cardiomyopathy hiPSC-Derived Cardiomyocytes upon Metabolic MaturationSemantic proximity Read ↗

Mitochondrial transplantation in cardiomyocytes: foundation, methods, and outcomesSemantic proximity Read ↗

Mitochondrial Transfer in Cardiovascular Disease: From Mechanisms to Therapeutic ImplicationsSemantic proximity Read ↗

Maturation of hiPSC-derived cardiomyocytes promotes adult alternative splicing of SCN5A and reveals changes in sodium current associated with cardiac arrhythmiaSemantic proximity Read ↗

Alpha protein kinase 3 gene therapy restores heart function in mouse and human models of cardiomyopathySemantic proximity Read ↗

Effects of increasing intranuclear calcium levels via MCU inhibition on iPSC-derived cardiomyocyte differentiation and maturationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.