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An outbreak of influenza A(H1N1)pdm09 antigenic variants exhibiting cross-resistance to oseltamivir and peramivir in an elementary school in Japan, September 2024.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 1 Dec 2024

Takashita Emi, Shimizu Kohei, Usuku Shuzo, Senda Ryuichi, Okubo Ichiro, Morita Hiroko, Nagata Shiho, Fujisaki Seiichiro, Miura Hideka, Kishida Noriko, Nakamura Kazuya, Shirakura Masayuki, Ichikawa Masataka, Matsuzaki Yoko, Watanabe Shinji, Takahashi Yoshimasa, Hasegawa Hideki

Abstract excerpt

An outbreak of influenza A(H1N1)pdm09 viruses exhibiting cross-resistance to oseltamivir and peramivir occurred in Yokohama, Japan, in September 2024. Among 24 students in a class, 11 were diagnosed with influenza or influenza-like illness, and viruses harbouring the NA H275Y and HA Q210H substitutions were isolated from four. Deep sequencing analysis confirmed the clonal spread of these mutants. Antigenic...

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Cyclopentanes
Disease Outbreaks
Guanidines
Influenza A Virus, H1N1 Subtype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Influenza, Human

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PMID: 39668762
DOI: 10.2807/1560-7917.ES.2024.29.50.2400786
PMCID: PMC11650510

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An outbreak of influenza A(H1N1)pdm09 antigenic variants exhibiting cross-resistance to oseltamivir and peramivir in an elementary school in Japan, September 2024.PMID 39668762Read ↗

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