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Article

Characterization of neuraminidase inhibitor-resistant influenza A(H1N1)pdm09 viruses isolated in four seasons during pandemic and post-pandemic periods in Japan.

Influenza and other respiratory viruses - 1 Nov 2013

Takashita Emi, Fujisaki Seiichiro, Kishida Noriko, Xu Hong, Imai Masaki, Tashiro Masato, Odagiri Takato

Abstract excerpt

BACKGROUND/OBJECTIVES: Japan has the highest frequency of neuraminidase (NA) inhibitor use against influenza in the world. Therefore, Japan could be at high risk of the emergence and spread of NA inhibitor-resistant viruses. The aim of this study was to monitor the emergence of NA inhibitor-resistant viruses and the possibility of human-to-human transmission during four influenza seasons in Japan. METHODS: To...

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Identifiers

PMID: 23745712
DOI: 10.1111/irv.12132
PMCID: PMC4634248

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