Article
Functional analysis of a t complex responder locus transgene in mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1992
Bullard D C, Ticknor C, Schimenti J C
Abstract excerpt
Transmission ratio distortion (TRD) of mouse t haplotypes occurs through the interaction of multiple distorter loci with the t complex responder (Tcr) locus. Males heterozygous for a t haplotype will transmit the t-bearing chromosome to nearly all of their offspring. This process is mediated by the production of functionally inequivalent gametes: wild-type meiotic partners of t spermatozoa are rendered...
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