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Article

Functional analysis of a t complex responder locus transgene in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1992

Bullard D C, Ticknor C, Schimenti J C

Abstract excerpt

Transmission ratio distortion (TRD) of mouse t haplotypes occurs through the interaction of multiple distorter loci with the t complex responder (Tcr) locus. Males heterozygous for a t haplotype will transmit the t-bearing chromosome to nearly all of their offspring. This process is mediated by the production of functionally inequivalent gametes: wild-type meiotic partners of t spermatozoa are rendered...

Topics

Animals
Chromosome Mapping
Cloning, Molecular
Female
Haplotypes
Intracellular Signaling Peptides and Proteins
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Microtubule-Associated Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nuclear Proteins

Phenotype

Ubiquitin-Protein Ligases

t-Complex Genome Region

Source

Identifiers

PMID: 1421767
DOI: 10.1007/BF00350625

Genes

TRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1421767-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Functional analysis of a t complex responder locus transgene in mice.PMID 1421767Read ↗

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