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Article

Segregation distortion of mouse t haplotypes the molecular basis emerges.

Trends in genetics : TIG - 1 Jun 2000

Schimenti J

Abstract excerpt

The t haplotype is an ancestral version of proximal mouse chromosome 17 that has evolved mechanisms to persist as an intact genomic variant in mouse populations. t haplotypes contain mutations that affect embryonic development, male fertility and male transmission ratio distortion (TRD). Collectively, these mutations drive the evolutionary success of t haplotypes, a phenomenon that remains one of the longstanding...

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Source

Identifiers

PMID: 10827448
DOI: 10.1016/s0168-9525(00)02020-5

Genes

TRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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