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Article

Models for male infertility: the t haplotypes.

Reviews of reproduction - 1 Sept 1997

Olds-Clarke P

Abstract excerpt

The t haplotypes are variant alleles of genes in the proximal region of mouse Chromosome 17, linked together by four inversions. While females carrying two t haplotypes are fertile, males are sterile. Their spermatozoa exhibit severe motility defects and are unable to penetrate zona pellucida-free oocytes. Spermatozoa from males carrying one t haplotype (t/+) exhibit mild motility deficits and a delay in...

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PMID: 9414479
DOI: 10.1530/ror.0.0020157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Models for male infertility: the t haplotypes.PMID 9414479Read ↗

Genes in the first and fourth inversions of the mouse t complex synergistically mediate sperm capacitation and interactions with the oocyte.Semantic proximity Read ↗

t haplotypes in the mouse compromise sperm flagellar function.Semantic proximity Read ↗

The molecular basis of "curlicue": a sperm motility abnormality linked to the sterility of t haplotype homozygous male mice.Semantic proximity Read ↗

Hybrid sterility-6: a mouse t complex locus controlling sperm flagellar assembly and movement.Semantic proximity Read ↗

[Sterility of males determined by functional features of the mouse spermatozoa bearing t-complex].Semantic proximity Read ↗

New insights into the t-complex and control of sperm function.Semantic proximity Read ↗

An additional type of male sterility and inherited urinary obstruction in mice with the t-haplotype th7.Semantic proximity Read ↗

Hst7: a male sterility mutation perturbing sperm motility, flagellar assembly, and mitochondrial sheath differentiation.Semantic proximity Read ↗

Deletion analysis of male sterility effects of t-haplotypes in the mouse.Semantic proximity Read ↗

Identification of a cryptic lethal mutation in the mouse t(w73) haplotype.Semantic proximity Read ↗

Sperm from mice carrying two t haplotypes do not possess a tyrosine phosphorylated form of hexokinase.Semantic proximity Read ↗

Segregation distortion of mouse t haplotypes the molecular basis emerges.Semantic proximity Read ↗

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