Analysis of genetic polymorphism and expression of SOX2 in oral leukoplakia: a case-control study.

doi:10.1016/j.oooo.2024.11.082

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Article

Analysis of genetic polymorphism and expression of SOX2 in oral leukoplakia: a case-control study.

Oral surgery, oral medicine, oral pathology and oral radiology - 1 Apr 2025

Scheifer Suelen Teixeira, Michels Arieli Carini, Modolo Filipe, Carla Dos Santos Emanuela, Scariot Rafaela, Aguiar Maria Cassia Ferreira, Ignácio Sergio Aparecido, de Noronha Lucia, Martins Laysa Toschi, Frigeri Henrique Ravanhol, de Souza Cleber Machado, Jham Bruno Correia, Marins Mariana Hornung, Johann Aline Cristina Batista Rodrigues

Abstract excerpt

PURPOSE: To investigate the association of SOX2 polymorphisms with oral leukoplakia with dysplasia (OLD) and compare it with the immunohistochemical expression of SOX-2. METHODS: The samples comprised 64 patients with oral leukoplakia and 20 with normal oral mucosa who were subjected to SOX2 polymorphism rs77677339 genotyping by real-time polymerase chain reaction and immunohistochemistry for SOX-2 (basal...

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PMID: 39648056
DOI: 10.1016/j.oooo.2024.11.082

Genes

SOX2

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