Article
Rs12941170 at SOX9 gene associated with orofacial clefts in Chinese.
Archives of oral biology - 1 Apr 2017
Jia Zhong-Lin, He Sha, Jiang Shu-Yuan, Zhang Bi-He, Duan Shi-Jun, Shi Jia-Yu, Huang Ning, Zhu Wen-Chao, Shi Bing
Abstract excerpt
OBJECTIVE: Non-syndromic orofacial cleftings (NSOCs) are considered as complex trait, which results from genetic and/or environmental modifiers. Current findings could only explain small portion of the NSOCs. SOX9 gene plays an important role during craniofacial development in animal models and the Pierre Robin sequence (PRS). However, its role in non-syndromic clefts remains unknown. DESIGN: In this study, we...
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