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Article

Genetic factors in the pathogenesis of ameloblastoma, dentigerous cyst and odontogenic keratocyst.

Gene - 1 Mar 2021

Ghafouri-Fard Soudeh, Atarbashi-Moghadam Saede, Taheri Mohammad

Abstract excerpt

Ameloblastoma (AB), dentigerous cyst (DC) and Odontogenic keratocyst (OKC) are odontogenic lesions with propensity to malignant transformation or local invasion. The molecular mechanisms of development of these lesions are not fully understood. However, some researches have reported dysregulation of tumor suppressor genes or oncogenes in these lesions. Down-regulation of P53 gene has been reported in AB, DC and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33346102
DOI: 10.1016/j.gene.2020.145369

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