Article
Association between MIR31HG polymorphisms and the risk of Lumbar disc herniation in Chinese Han population.
Cell cycle (Georgetown, Tex.) - 1 Oct 2022
Hu Xinglv, Hao Dingjun, Yin Jichao, Gong Futai, Wang Xiangyang, Wang Ruoxi, Liu Bo
Abstract excerpt
Lumbar disc herniation (LDH) is a common spinal disease that endangers human health. Genetic factors play a vital role in the progression of LDH. This study aimed to explore the relationship of the MIR31HG polymorphism with LDH risk in the Chinese population. Seven candidate SNPs on MIR31HG in 504 patients with LDH and 503 healthy people were genotyped by Agena MassARRAY platform. Logistic regression was used to...
Topics
- Case-Control Studies
- China
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Intervertebral Disc Displacement
- Lumbar Vertebrae
- Male
- Polymorphism, Single Nucleotide
