Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Extracellular Matrix as a Target in Melanoma Therapy: From Hypothesis to Clinical Trials

19 Nov 2024

Abstract excerpt

Melanoma is a malignant, highly metastatic neoplasm showing increasing morbidity and mortality. Tumor invasion and angiogenesis are based on remodeling of the extracellular matrix (ECM). Selective inhibition of functional components of cell-ECM interaction, such as hyaluronic acid (HA), matrix metalloproteinases (MMPs), and integrins, may inhibit tumor progression and enhance the efficacy of combination treatment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cell Adhesion Molecules Research
Share to Cellular Mechanics and Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39594665
DOI: 10.3390/cells13221917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Extracellular Matrix as a Target in Melanoma Therapy: From Hypothesis to Clinical TrialsPMID 39594665Read ↗

Role of extracellular matrix architecture and signaling in melanoma therapeutic resistanceSemantic proximity Read ↗

Microenvironment and tumor progression of melanoma: New therapeutic prospectivesSemantic proximity Read ↗

BRAF V600-Mutated Metastatic Melanoma and Targeted Therapy Resistance: An Update of the Current KnowledgeSemantic proximity Read ↗

Melanoma and the tumor microenvironment.Semantic proximity Read ↗

Targeted therapeutic strategies for melanoma.Semantic proximity Read ↗

Recent developments in the medical and surgical treatment of melanoma.Semantic proximity Read ↗

Harnessing Extracellular Matrix Biology for Tumor Drug DeliverySemantic proximity Read ↗

Surgical Management of Stage IV Melanoma: Clinical, Molecular, and Therapeutic Considerations.Semantic proximity Read ↗

Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatmentsSemantic proximity Read ↗

Molecular therapy for melanoma: useful and not useful targets.Semantic proximity Read ↗

The extracellular matrix alteration, implication in modulation of drug resistance mechanism: friends or foes?Semantic proximity Read ↗

The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and MetastasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.