Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Understanding the biological processes of kidney carcinogenesis: an integrative multi-omics approach.

Molecular systems biology - 1 Dec 2024

Cortez Cardoso Penha Ricardo, Sexton Oates Alexandra, Senkin Sergey, Park Hanla A, Atkins Joshua, Holcatova Ivana, Hornakova Anna, Savic Slavisa, Ognjanovic Simona, Świątkowska Beata, Lissowska Jolanta, Zaridze David, Mukeria Anush, Janout Vladimir, Chabrier Amelie, Cahais Vincent, Cuenin Cyrille, Scelo Ghislaine, Foll Matthieu, Herceg Zdenko, Brennan Paul, Smith-Byrne Karl, Alcala Nicolas, Mckay James D

Abstract excerpt

Biological mechanisms related to cancer development can leave distinct molecular fingerprints in tumours. By leveraging multi-omics and epidemiological information, we can unveil relationships between carcinogenesis processes that would otherwise remain hidden. Our integrative analysis of DNA methylome, transcriptome, and somatic mutation profiles of kidney tumours linked ageing, epithelial-mesenchymal transition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

Share to Glutathione S-Transferase pi

Share to Histone-Lysine N-Methyltransferase

Share to Kidney Neoplasms

Share to Multiomics

Share to Tumor Suppressor Proteins

Share to Ubiquitin Thiolesterase

Source

Open in PubMed Open full text

Identifiers

PMID: 39592856
DOI: 10.1038/s44320-024-00072-3
PMCID: PMC11612429

Genes

BAP1
GSTP1
IL20RB
PBRM1
SETD2
WT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Understanding the biological processes of kidney carcinogenesis: an integrative multi-omics approach.PMID 39592856Read ↗

Disease aetiology and progression shape the inter-patient multi-omics profile of clear cell renal carcinomaSemantic proximity Read ↗

The Epigenetics of Renal Cell Tumors: from Biology to BiomarkersSemantic proximity Read ↗

Potential role of genetic markers in the management of kidney cancer.Semantic proximity Read ↗

Recent developments in epigenetics of acute and chronic kidney diseasesSemantic proximity Read ↗

Distinct functions of <i>PBRM1</i> and <i>BAP1</i> reconcile the course of kidney cancer evolution and disease progressionSemantic proximity Read ↗

Geographic variation of mutagenic exposures in kidney cancer genomes.Semantic proximity Read ↗

Systemic mutagen exposures reported by normal kidney cell genomesSemantic proximity Read ↗

The epigenetic landscape of renal cancer.Semantic proximity Read ↗

Evidence for the involvement of epigenetics in the progression of renal fibrogenesisSemantic proximity Read ↗

Unraveling the epigenetic landscape of glomerular cells in kidney diseaseSemantic proximity Read ↗

Renal Cell Cancer and ObesitySemantic proximity Read ↗

Sexual dimorphism in cancer: insights from transcriptional signatures in kidney tissue and renal cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.