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Hydroxysafflor yellow A ameliorates high-fat diet-induced hyperlipidemia by attenuating hepatic lipotoxicity and partially restoring the gut microbiota–intestinal barrier axis

2026-05-28

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Hyperlipidemia is a major risk factor for cardiovascular diseases. Accumulating evidence has demonstrated that the gut microbiota-liver axis exerts a crucial regulatory effect on lipid metabolism. Hydroxysafflor yellow A (HSYA), a major bioactive compound derived from <italic>Carthamus tinctorius</italic> L., exhibits anti-inflammatory and antioxidant proper...

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Literature Corpus work
46155026-c41e-599d-9846-1f8fbbb1af18
DOI
10.21203/rs.3.rs-9650845/v1
Open publication

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