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Article

Larsucosterol: endogenous epigenetic regulator for treating chronic and acute liver diseases

21 Feb 2024

Abstract excerpt

Larsucosterol, a potent endogenous epigenetic regulator, has been reported to play a significant role in lipid metabolism, inflammatory responses, and cell survival. The administration of larsucosterol has demonstrated a reduction in lipid accumulation within hepatocytes and the attenuation of inflammatory responses induced by lipopolysaccharide (LPS) and TNFα in macrophages, alleviating LPS- and acetaminophen...

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PMID: 38381400
DOI: 10.1152/ajpendo.00406.2023

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