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Article

Adaptive NKG2C+ NK Cell Response and the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2017

Redondo-Pachón Dolores, Crespo Marta, Yélamos Jose, Muntasell Aura, Pérez-Sáez María José, Pérez-Fernández Silvia, Vila Joan, Vilches Carlos, Pascual Julio, López-Botet Miguel

Abstract excerpt

CMV infection in kidney transplant recipients (KTRs) has been associated with an increased risk for graft loss and reduced host survival. CMV promotes persistent expansions of NK cells expressing the CD94/NKG2C receptor. The NKG2C (KLRC2) gene is frequently deleted, and copy number influences the adaptive response of NKG2C+ NK cells. The distribution of NKG2C+ NK cells and NKG2C genotypes (NKG2C+/+, NKG2C+/del,...

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Share to Adaptive Immunity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27913630
DOI: 10.4049/jimmunol.1601236

Genes

KLRC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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Adaptive NKG2C+ NK Cell Response and the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.PMID 27913630Read ↗

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