Calculating Future 10-Year Breast Cancer Risks in Risk-Adapted Surveillance: A Method Comparison and Application in Clinical Practice.

doi:10.1158/1940-6207.CAPR-24-0328

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Calculating Future 10-Year Breast Cancer Risks in Risk-Adapted Surveillance: A Method Comparison and Application in Clinical Practice.

Cancer prevention research (Philadelphia, Pa.) - 3 Feb 2025

Zachariae Silke, Quante Anne S, Kiechle Marion, Rhiem Kerstin, Fehm Tanja N, Schröder Jörg-Gunther, Horvath Judit, Leinert Elena, Dikow Nicola, Ronez Joelle, Schönfeld Mirjam, van Mackelenbergh Marion T, Schatz Ulrich A, Meisel Cornelia, Aktas Bahriye, Witt Dennis, Mehraein Yasmin, Weber Bernhard H F, Solbach Christine, Speiser Dorothee, Hoyer Juliane, Faigle-Krehl Gesine, Much Christiane D, Müller-Rausch Alma-Verena, Villavicencio-Lorini Pablo, Banys-Paluchowski Maggie, Pieh Daniel, Schmutzler Rita K, Fischer Christine, Engel Christoph

Abstract excerpt

The German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) has successfully implemented risk-adapted breast cancer surveillance for women at high breast cancer risk in Germany. Women with a family history of breast and ovarian cancer but without pathogenic germline variants in recognized breast cancer risk genes are recommended annual breast imaging if their predicted 10-year breast cancer risk is...

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PMID: 39575650
DOI: 10.1158/1940-6207.CAPR-24-0328
PMCID: PMC11788646

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