Article
Elevated serum aminotransferase induced by isoniazid in relation to isoniazid acetylator phenotype.
Hepatology (Baltimore, Md.) - 1 Jan 2000
Yamamoto T, Suou T, Hirayama C
Abstract excerpt
Of 143 patients with pulmonary tuberculosis receiving isoniazid therapy, 52 (36%) had a transient elevation in serum aminotransferases. Among 74 patients taking isoniazid, rifampicin and streptomycin, 35 (47%) had such an increase, while of 69 patients taking isoniazid, amino-salicylic acid and streptomycin, 17 (24%) did; this difference was significant. Isoniazid therapy could be continued in all patients with...
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