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Article

Evaluating the causal effects between Grave's disease and diabetes mellitus: a bidirectional Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Zhang Yuhan, Fu Liuxiang

Abstract excerpt

Background: Graves' disease (GD) is an autoimmune disease associated with an increased incidence of other autoimmune diseases. To investigate the causality between GD and Diabetes mellitus (DM), we designed bidirectional two-sample Mendelian randomization (MR) and multivariable MR (MVMR) studies. Methods: Single-nucleotide polymorphisms (SNPs) associated with GD, thyroid peroxidase (TPO), thyroglobulin (Tg),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39568808
DOI: 10.3389/fendo.2024.1420499
PMCID: PMC11576183

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