Article
The Causal Relationship between Genetically Predicted Biological Aging, Alzheimer's Disease and Cognitive Function: A Mendelian Randomisation Study.
The journal of prevention of Alzheimer's disease - 1 Jan 2024
Hao Y, Tian W, Xie B, Fu X, Wang S, Yang Y
Abstract excerpt
Aging is one of the most important risk factors for Alzheimer's disease (AD). Biological aging is a better indicator of the body's functional state than age (chronological aging). Leukocyte telomere length (LTL) and epigenetic clocks constructed from DNA methylation patterns have emerged as reliable markers of biological aging. Recent studies have shown that it may be possible to slow down or even reverse...
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