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Article

The effect of epigenetic aging on neurodegenerative diseases: a Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Fan Jingqi, Liu Qing, Liu Xin, Gong Mengjiao, Leong Ian I, Tsang YauKeung, Xu Xiaoyan, Lei Suying, Duan Lining, Zhang Yifan, Liao Muxi, Zhuang Lixing

Abstract excerpt

Background: Aging has always been considered as a risk factor for neurodegenerative diseases, but there are individual differences and its mechanism is not yet clear. Epigenetics may unveil the relationship between aging and neurodegenerative diseases. Methods: Our study employed a bidirectional two-sample Mendelian randomization (MR) design to assess the potential causal association between epigenetic aging and...

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Identifiers

PMID: 38800486
DOI: 10.3389/fendo.2024.1372518
PMCID: PMC11116635

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