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Article

Associations between post-traumatic stress disorder and neurological disorders: A genetic correlation and Mendelian randomization study.

Journal of affective disorders - 1 Feb 2025

Li Mingxi, Qu Kang, Wang Yueyuan, Wang Yongchun, Shen Yanxin, Sun Li

Abstract excerpt

BACKGROUND: Observational studies have reported a close relationship between post-traumatic stress disorder (PTSD) and neurological disorders, but the existence of a causal link remains uncertain. The aim of this study is to investigate these relationships and potential mediators via Mendelian randomization (MR) analysis. METHODS: We sourced pooled data for genome-wide association study (GWAS) of PTSD...

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PMID: 39547276
DOI: 10.1016/j.jad.2024.11.044

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