Article
Pheochromocytoma and paraganglioma: molecular testing and personalized medicine.
Current opinion in oncology - 1 Jan 2016
Burnichon Nelly, Buffet Alexandre, Gimenez-Roqueplo Anne-Paule
Abstract excerpt
PURPOSE OF REVIEW: Pheochromocytomas and paragangliomas (PPGLs) are rare tumours, strongly associated with inherited susceptibility gene mutations, and presenting limited therapeutic options for patients with metastatic disease. This review discusses the recent developments in the characterization of PPGL genetic heterogeneity and associated tumorigenesis pathways, together with their potential clinical...
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