Article
A Single Nucleotide Polymorphism in Catalase Is Strongly Associated with Ovarian Cancer Survival.
PloS one - 1 Jan 2015
Belotte Jimmy, Fletcher Nicole M, Saed Mohammed G, Abusamaan Mohammed S, Dyson Gregory, Diamond Michael P, Saed Ghassan M
Abstract excerpt
Ovarian cancer is the deadliest of all gynecologic cancers. Recent evidence demonstrates an association between enzymatic activity altering single nucleotide polymorphisms (SNP) with human cancer susceptibility. We sought to evaluate the association of SNPs in key oxidant and antioxidant enzymes with increased risk and survival in epithelial ovarian cancer. Individuals (n = 143) recruited were divided into...
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