Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic and transcriptomic profiling of induced pluripotent stem cell (iPSC)-derived NK cells and their cytotoxicity against cancers.

Stem cell research & therapy - 13 Nov 2024

Thongsin Nontaphat, Suwanpitak Siriwal, Augsornworawat Punn, Srisantitham Jakkrapatra, Saiprayong Kritayaporn, Jenjaroenpun Piroon, Wattanapanitch Methichit

Abstract excerpt

BACKGROUND: Adoptive immunotherapy using natural killer (NK) cells has attracted considerable interest in numerous clinical trials targeting both hematological and solid tumors. Traditionally, NK cells are primarily derived from either peripheral blood (PB) or umbilical cord blood (UCB). However, these methods can lead to variability and heterogeneity within the NK cell population. In contrast, induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Immunotherapy, Adoptive

Share to Induced Pluripotent Stem Cells

Share to Killer Cells, Natural

Share to Neoplasms

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 39533434
DOI: 10.1186/s13287-024-04029-z
PMCID: PMC11559060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic and transcriptomic profiling of induced pluripotent stem cell (iPSC)-derived NK cells and their cytotoxicity against cancers.PMID 39533434Read ↗

Comparative analysis of iPSC-derived NK cells from two differentiation strategies reveals distinct signatures and cytotoxic activitiesSemantic proximity Read ↗

Engineered iPSC ‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapySemantic proximity Read ↗

iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti–PD-1 therapySemantic proximity Read ↗

Genome engineering of induced pluripotent stem cells to manufacture natural killer cell therapiesSemantic proximity Read ↗

An Alternative Cell Therapy for Cancers: Induced Pluripotent Stem Cell (iPSC)-Derived Natural Killer CellsSemantic proximity Read ↗

Multiplexed iPSC platform for advanced NK cell immunotherapiesSemantic proximity Read ↗

Generation of dual-attribute iTNK cells from hPSCs for cancer immunotherapySemantic proximity Read ↗

iPSC-Derived Natural Killer Cells for Cancer ImmunotherapySemantic proximity Read ↗

Engineered and banked iPSCs for advanced NK- and T-cell immunotherapiesSemantic proximity Read ↗

Induced Pluripotent Stem Cell (iPSC)–Derived Lymphocytes for Adoptive Cell Immunotherapy: Recent Advances and ChallengesSemantic proximity Read ↗

An improved method to produce clinical scale natural killer cells from human pluripotent stem cellsSemantic proximity Read ↗

Genetically stable multi-gene edited iPSCs-derived NK cells for enhanced cancer immunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.